About a year ago I wrote about hosting a Node.js application via IIS. It uses IIS as a reversed proxy to route traffic from IIS to the node.js webserver. To manage the node.js process pm2 was used. Unfortunately I had some problems restarting the pm2 process when the server restarted. This meant downtime everytime the server was restarted until I manually resurrected pm2.
Unfortunately a lot of companies are still stuck with Windows servers. Nobody ever got fired for choosing Microsoft, right. As a developer this can be frustrating because choosing a server technology is usually limited to ASP.Net. I have experimented with hosting Node.js applications on a Windows server by using iisnode. But it is a pain to get up and running, setting the correct permissions is a time consuming chore. Microsoft has taken control of the development of the project but I get the feeling it's not very active any more. There are several Stackoverflow questions where people just give up configuring it.